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GPR4 Polyklonaler Antikörper

GPR4 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28232-1-PBS

Synonyme

G protein coupled receptor 4, G-protein coupled receptor 4, G-protein coupled receptor 6C.l

Filter:
  • Immunohistochemistry (IHC) staining of mouse lung tissue using GPR4 Polyclonal antibody (28232-1-AP)

    IHC staining of mouse lung using 28232-1-AP (same clone as 28232-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 28232-1-AP (GPR4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28232-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse kidney tissue using GPR4 Polyclonal antibody (28232-1-AP)

    IHC staining of mouse kidney using 28232-1-AP (same clone as 28232-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 28232-1-AP (GPR4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28232-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28232-1-PBS bindet in IHC, Indirect ELISA GPR4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen GPR4 fusion protein Ag28273
Vollständiger Name G protein-coupled receptor 4
Berechnetes Molekulargewicht 362 aa, 41 kDa
GenBank-ZugangsnummerBC067535
Gene symbol GPR4
Gene ID (NCBI) 2828
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GPR4 (G-protein-coupled receptor 4) is a proton-sensing G-protein-coupled receptor (GPCR) that contributes to neovascularization in acidic microenvironments (PMID: 33632325). GPR4 is highly expressed in vascular endothelial cells (ECs) and blood vessel-rich tissues such as the lung, kidney, heart, and liver. Moreover, GPR4 has been shown to mediate EC inflammatory responses to acidosis and is central for leukocyte-endothelium interaction (PMID: 27940273).