Glutamate receptor 3/GluA3 Polyklonaler Antikörper

Glutamate receptor 3/GluA3 Polyklonal Antikörper für WB, IF-P, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF-P, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29588-1-PBS

Synonyme

GRIA3, GLURC, GLUR3, GLUR K3, GLUR C

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  WB analysis using 29588-1-AP (same clone as 29588-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29588-1-AP (Glutamate receptor 3/GluA3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  WB analysis using 29588-1-AP (same clone as 29588-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29588-1-AP (GRIA3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 29588-1-AP (same clone as 29588-1-PBS)

  IP result of anti-GRIA3 (IP:29588-1-AP, 4ug; Detection:29588-1-AP 1:1000) with mouse brain tissue lysate 1280 ug. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 29588-1-AP (same clone as 29588-1-PBS)

  IP result of anti-Glutamate receptor 3/GluA3 (IP:29588-1-AP, 4ug; Detection:29588-1-AP 1:2000) with mouse brain tissue lysate 1280 ug. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 29588-1-AP (same clone as 29588-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using Glutamate receptor 3/GluA3 antibody (29588-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IF Staining of rat brain using 29588-1-AP (same clone as 29588-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using Glutamate receptor 3/GluA3 antibody (29588-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

29588-1-PBS bindet in WB, IF-P, IP, Indirect ELISA Glutamate receptor 3/GluA3 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Glutamate receptor 3/GluA3 fusion protein Ag30898
• Vollständiger Name: glutamate receptor, ionotrophic, AMPA 3
• Berechnetes Molekulargewicht: 101 kDa
• Beobachtetes Molekulargewicht: 101 kDa
• GenBank-Zugangsnummer: NM_007325
• Gene symbol: GRIA3
• Gene ID (NCBI): 2892
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GRIA3 (Glutamate ionotropic receptor AMPA type subunit 3), also known as Glutamate receptor R3 or A3 (GluR3 or GluA3), is associated with X-linked intellectual disability (ID), dysmorphic features, and non-syndromic epilepsy(PMID: 32977175). GRIA3 also plays a role as a mediator of tumor progression in pancreatic cancer downstream CUX1(PMID: 20689760).