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ProGRP Polyklonaler Antikörper

ProGRP Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (1)

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 14646-1-AP

Synonyme

BN, gastrin releasing peptide, GRP, GRP 10, preproGRP, proGRP

Filter:
  • Western Blot (WB) analysis of Transfected HEK-293 cells using ProGRP Polyclonal antibody (14646-1-AP)

    WB analysis of Transfected HEK-293 using 14646-1-AP

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 14646-1-AP (ProGRP antibody at dilution of 1:500 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Veröffentlichte Anwendungen

IHCSee 1 publications below

Produktinformation

14646-1-AP bindet in IHC, ELISA ProGRP und zeigt Reaktivität mit human

Getestete Reaktivität human
In Publikationen genannte ReaktivitätSchimpanse
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ProGRP fusion protein Ag6239
Vollständiger Name gastrin-releasing peptide
Berechnetes Molekulargewicht 16 kDa
GenBank-ZugangsnummerBC004488
Gene symbol GRP
Gene ID (NCBI) 2922
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.

Publikationen

SpeciesApplicationTitle
chimpanzeeIHC

Brain Struct Funct

The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans.

Authors - Allman John M JM
View Article