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GSDMA Polyklonaler Antikörper

GSDMA Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30354-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using GSDMA Polyclonal antibody (30354-1-AP)

    WB analysis using 30354-1-AP (same clone as 30354-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30354-1-AP (GSDMA antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30354-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30354-1-PBS bindet in WB, Indirect ELISA GSDMA und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen GSDMA fusion protein Ag31284
Vollständiger Name gasdermin A
Berechnetes Molekulargewicht 445 aa, 49 kDa
Beobachtetes Molekulargewicht49 kDa
GenBank-ZugangsnummerBC109197
Gene symbol GSDMA
Gene ID (NCBI) 284110
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.