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GSDMA Rekombinanter Antikörper

GSDMA Rekombinant Antikörper für Indirect ELISA, WB

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

Indirect ELISA, WB

Konjugation

Unkonjugiert

CloneNo.

230161D4

Kat-Nr. : 82920-1-PBS

Synonyme

Gasdermin-A, Gasdermin-1, gasdermin A, Gasdermin 1, FKSG9

Filter:
  • Western Blot (WB) analysis of Daudi cells using GSDMA Recombinant antibody (82920-1-RR)

    WB analysis of Daudi using 82920-1-RR (same clone as 82920-1-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 82920-1-RR (GSDMA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82920-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82920-1-RR

    Affinity and Kinetic Characterization of 82920-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82920-1-RR against Human GSDMA were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

82920-1-PBS bindet in Indirect ELISA, WB GSDMA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen GSDMA fusion protein Ag24407
Vollständiger Name gasdermin A
Berechnetes Molekulargewicht 445 aa, 49 kDa
Beobachtetes Molekulargewicht49 kDa
GenBank-ZugangsnummerBC109197
Gene symbol GSDMA
Gene ID (NCBI) 284110
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.