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GSDMA Rekombinanter Antikörper

GSDMA Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230161C5

Kat-Nr. : 82920-2-PBS

Synonyme

Gasdermin-A, Gasdermin-1, gasdermin A, Gasdermin 1, FKSG9

Filter:
  • Western Blot (WB) analysis of various lysates using GSDMA Recombinant antibody (82920-2-RR)

    WB analysis using 82920-2-RR (same clone as 82920-2-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 82920-2-RR (GSDMA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82920-2-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using GSDMA Recombinant antibody (82920-2-RR)

    IF Staining of HeLa using 82920-2-RR (same clone as 82920-2-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using GSDMA antibody (82920-2-RR, Clone: 230161C5 ) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 82920-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82920-2-RR

    Affinity and Kinetic Characterization of 82920-2-RR

    Biolayer interferometry (BLl) kinetic assays of 82920-2-RR against Human GSDMA were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

82920-2-PBS bindet in WB, IF/ICC, Indirect ELISA GSDMA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen GSDMA fusion protein Ag24407
Vollständiger Name gasdermin A
Berechnetes Molekulargewicht 445 aa, 49 kDa
Beobachtetes Molekulargewicht49 kDa
GenBank-ZugangsnummerBC109197
Gene symbol GSDMA
Gene ID (NCBI) 284110
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.