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GSDMC Polyklonaler Antikörper

GSDMC Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30469-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using GSDMC Polyclonal antibody (30469-1-AP)

    WB analysis using 30469-1-AP (same clone as 30469-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30469-1-AP (GSDMC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using GSDMC Polyclonal antibody (30469-1-AP)

    WB analysis using 30469-1-AP (same clone as 30469-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30469-1-AP (GSDMC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of Human bowens disease using GSDMC Polyclonal antibody (30469-1-AP)

    IHC staining of Human bowens disease using 30469-1-AP (same clone as 30469-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brown disease slide using 30469-1-AP (GSDMC antibody) at dilution of 1:600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30469-1-PBS bindet in WB, IHC, Indirect ELISA GSDMC und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen GSDMC fusion protein Ag33319
Vollständiger Name gasdermin C
Berechnetes Molekulargewicht58kd
Beobachtetes Molekulargewicht58 kDa
GenBank-ZugangsnummerNM_031415
Gene symbol GSDMC
Gene ID (NCBI) 56169
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Gasdermin (GSDM) superfamily consists of Gasdermin family genes (GSDMA, GSDMB, GSDMC and GSDMD in humans) and Gasdermin-related genes (DFNA5, DFNB59 in humans). GSDM family members were shown to be detected in the epithelium of various tissue types in a highly tissue-specific manner and suggested to have differentiation-status specific roles. Gasdermin C (GSDMC) was known as melanoma-derived leucine zipper-containing extranuclear factor (MLZE). Several studies have suggested that GSDMC may be involved in the course of tumorigenesis such as acquisition of metastatic potential in melanoma cells or promotion of cell proliferation in colorectal carcinogenesis and that GSDMC may function as an oncogene. (PMID: 29428815)