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GSTP1 Rekombinanter Antikörper

GSTP1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251705C10

Kat-Nr. : 86708-1-PBS

Synonyme

EC:2.5.1.18, FAEES3, Glutathione S-transferase P, GST3, GST3/GST pi

Filter:
  • Western Blot (WB) analysis of various lysates using GSTP1 Recombinant monoclonal antibody (86708-1-RR)

    WB analysis using 86708-1-RR (same clone as 86708-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86708-1-RR (GSTP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86708-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86708-1-RR

    Affinity and Kinetic Characterization of 86708-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86708-1-RR against Human GSTP1 were performed. The affinity constant is 5.60 nM.

Geprüfte Anwendungen

Produktinformation

86708-1-PBS bindet in WB, Indirect ELISA GSTP1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen GSTP1 fusion protein Ag8731
Vollständiger Name glutathione S-transferase pi 1
Berechnetes Molekulargewicht 210 aa, 23 kDa
Beobachtetes Molekulargewicht23~28 kDa
GenBank-ZugangsnummerBC010915
Gene symbol GSTP1
Gene ID (NCBI) 2950
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Glutathione S-transferase Pi (GSTP1) is anisozyme encoded by the GST pi gene that plays an importantregulatory role in detoxification, anti‑oxidative damage, and the occurrence of various diseases (PMID: 14755684). GSTP1 conjugates reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. It is involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PMID:9084911). GSTP1 methylation is frequently associated with tumor development or poor prognosis in a wide range of tumors such as neuroblastoma, hepatocellular carcinoma, endometrial, breast, and prostate cancers (PCa) (PMID: 27594734).