GTPBP10 Polyklonaler Antikörper

GTPBP10 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32944-1-PBS

Synonyme

GTP-binding protein 10, ObgH2, Protein obg homolog 2, UG0751c10

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  WB analysis using 32944-1-AP (same clone as 32944-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32944-1-AP (GTPBP10 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32944-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32944-1-PBS bindet in WB, Indirect ELISA GTPBP10 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: GTPBP10 fusion protein Ag37974
• Vollständiger Name: GTP-binding protein 10 (putative)
• Berechnetes Molekulargewicht: 43, 34, 12 kDa
• Beobachtetes Molekulargewicht: 42, 34, 20 kDa
• GenBank-Zugangsnummer: BC107714
• Gene symbol: GTPBP10
• Gene ID (NCBI): 85865
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GTPBP10, a member of the conserved Obg family of P-loop small G proteins, is a mitochondrial protein. The absence of GTPBP10 leads to attenuated mtLSU and mtSSU levels and the virtual absence of the 55S monosome, which entirely prevents mitochondrial protein synthesis. GTPBP10 physically interacts with the 16S rRNA, but not with the 12S rRNA, and crosslinks with several mtLSU proteins. Additionally, GTPBP10 is indirectly required for efficient processing of the 12S-16S rRNA precursor transcript, which could explain the mtSSU accumulation defect (PMID: 30321378).