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GUCY2C Monoklonaler Antikörper

GUCY2C Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1F5F6

Kat-Nr. : 67782-1-PBS

Synonyme

GC C, Guanylyl cyclase C, GUC2C, GUCY2C, hSTAR, Intestinal guanylate cyclase, STA receptor, STAR

Filter:
  • Western Blot (WB) analysis of Caco-2 cells using GUCY2C Monoclonal antibody (67782-1-Ig)

    WB analysis of Caco-2 using 67782-1-Ig (same clone as 67782-1-PBS)

    Caco-2 cells were subjected to SDS PAGE followed by western blot with 67782-1-Ig (GUCY2C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67782-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HaCaT cells using GUCY2C Monoclonal antibody (67782-1-Ig)

    WB analysis of HaCaT using 67782-1-Ig (same clone as 67782-1-PBS)

    HaCaT cells were subjected to SDS PAGE followed by western blot with 67782-1-Ig (GUCY2C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67782-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using GUCY2C Monoclonal antibody (67782-1-Ig)

    WB analysis of HeLa using 67782-1-Ig (same clone as 67782-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67782-1-Ig (GUCY2C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67782-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67782-1-PBS bindet in WB, Indirect ELISA GUCY2C und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen GUCY2C fusion protein Ag19256
Vollständiger Name guanylate cyclase 2C (heat stable enterotoxin receptor)
Berechnetes Molekulargewicht 1073 aa, 123 kDa
Beobachtetes Molekulargewicht130 kDa
GenBank-ZugangsnummerBC136544
Gene symbol GUCY2C
Gene ID (NCBI) 2984
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GUCY2C is also named as GUC2C, STAR(Heat-stable enterotoxin receptor), Guanylyl cyclase C and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the E.coli heat-stable enterotoxin and considered to be the true apical membrane receptor for the endogenous ligands uroguanylin and guanylin. GUCY2C is not present in the endocrine pancreas, but is localized exclusively to the ductal system which fully corresponds to the GUCY2C activity detected in the exocrine ductal system, but particularly not in islets of Langerhans. GUCY2C with a molecular mass of 130 kDa is detected in pancreatic and intestinal extracts.(PMID:11431160). The full length protein is 123 kDa and has a signal peptide and nine glycosylation sites.