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GUCY2D Polyklonaler Antikörper

GUCY2D Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55127-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using GUCY2D Polyclonal antibody (55127-1-AP)

    WB analysis of mouse brain using 55127-1-AP (same clone as 55127-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 55127-1-AP (GUCY2D antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55127-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human brain tissue using GUCY2D Polyclonal antibody (55127-1-AP)

    WB analysis of human brain using 55127-1-AP (same clone as 55127-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 55127-1-AP (GUCY2D antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55127-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human brain tissue using GUCY2D Polyclonal antibody (55127-1-AP)

    WB analysis of human brain using 55127-1-AP (same clone as 55127-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 55127-1-AP (GUCY2D antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55127-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55127-1-PBS bindet in WB, Indirect ELISA GUCY2D und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name guanylate cyclase 2D, membrane (retina-specific)
Berechnetes Molekulargewicht 120 kDa
Beobachtetes Molekulargewicht 120 kDa, 95 kDa
GenBank-ZugangsnummerNM_000180
Gene symbol GUCY2D
Gene ID (NCBI) 3000
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GUCY2D, also named as CORD6, GUC1A4, GUC2D, RETGC, RETGC1 and ROS-GC, belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. A number of nonsense and frameshift mutations in the GUCY2D gene have been identified in LCA1 patients. Defects in GUCY2D are the cause of cone-rod dystrophy type 6 (CORD6). GUCY2D is responsible for many reported cases of autosomal dominant CRDs. The antibody is specific to GUCY2D.