Glucocorticoid receptor Rekombinanter Antikörper
Glucocorticoid receptor Rekombinant Antikörper für WB, IHC, IF/ICC, IP, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, IHC, IF/ICC, IP, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2F22
Kat-Nr. : 82619-4-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
82619-4-PBS bindet in WB, IHC, IF/ICC, IP, Indirect ELISA Glucocorticoid receptor und zeigt Reaktivität mit human, Maus
Getestete Reaktivität | human, Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Glucocorticoid receptor fusion protein Ag21146 |
Vollständiger Name | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
Berechnetes Molekulargewicht | 86 kDa |
Beobachtetes Molekulargewicht | 94-97 kDa |
GenBank-Zugangsnummer | BC015610 |
Gene symbol | Glucocorticoid receptor |
Gene ID (NCBI) | 2908 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is a receptor for glucocorticoids, which owns a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. It is involved in cell proliferation and differentiation and specifically implicated in newborn birth weight, thus providing a biological mechanism by which NR3C1 expression may influence birth weight (PMID:22810058).