Glutamine synthetase Rekombinanter Antikörper

Glutamine synthetase Rekombinant Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251711A8

Kat-Nr. : 86716-1-PBS

Synonyme

GLUL, EC:2.3.1.225, EC:6.3.1.2, GLNS, Glutamate--ammonia ligase

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  WB analysis using 86716-1-RR (same clone as 86716-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86716-1-RR (Glutamine synthetase antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86716-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 86716-1-RR (same clone as 86716-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86716-1-RR (Glutamine synthetase antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86716-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse liver using 86716-1-RR (same clone as 86716-1-PBS)

  IP result of anti-Glutamine synthetase (IP:86716-1-RR, 4ug; Detection:86716-1-RR 1:2000) with mouse liver tissue lysate 2480 ug. This data was developed using the same antibody clone with 86716-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

86716-1-PBS bindet in WB, IP, Indirect ELISA Glutamine synthetase und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Glutamine synthetase fusion protein Ag1510
• Vollständiger Name: glutamate-ammonia ligase (glutamine synthetase)
• Berechnetes Molekulargewicht: 374 aa, 42 kDa
• Beobachtetes Molekulargewicht: 40-42 kDa
• GenBank-Zugangsnummer: BC011700
• Gene symbol: Glutamine Synthetase
• Gene ID (NCBI): 2752
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GLUL(Glutamine synthetase) is also named as GS,GLNS and belongs to the glutamine synthetase family. This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner By similarity. Essential for proliferation of fetal skin fibroblasts(PMID:18662667).Defects in GLUL are the cause of congenital systemic glutamine deficiency (CSGD).Organismal glutamine production is augmented secondary to an increase in the activity of glutamine synthetase in the lung and skeletal muscle(PMID:7630137).