• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Glypican 2 Polyklonaler Antikörper

Glypican 2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13521-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using Glypican 2 Polyclonal antibody (13521-1-AP)

    WB analysis using 13521-1-AP (same clone as 13521-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13521-1-AP (Glypican 2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13521-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using Glypican 2 Polyclonal antibody (13521-1-AP)

    WB analysis using 13521-1-AP (same clone as 13521-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13521-1-AP (Glypican 2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13521-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13521-1-PBS bindet in WB, Indirect ELISA Glypican 2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Glypican 2 fusion protein Ag4041
Vollständiger Name glypican 2
Berechnetes Molekulargewicht 579 aa, 63 kDa
Beobachtetes Molekulargewicht62，70-100 kDa
GenBank-ZugangsnummerBC027972
Gene symbol GPC2
Gene ID (NCBI) 221914
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Glypican 2 (GPC2) is a heparan sulfate proteoglycan that is linked to the outer leaflet of the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage(PMID: 18505598). It is expected to be located in cell membrane and highly overexpressed in a high percentage of human neuroblastomas, medulloblastomas, and retinoblastomas. The calculated molecular weight of GPC2 is 62 kDa. And other bands are the result of glycosylation modification. Recent studies demonstrate that expression of the GPC2 protein is significantly increased in neuroblastoma and undetectable in normal tissues, including brain, heart, lung, and kidney, indicating that GPC2 is a suitable tumor antigen in neuroblastoma (PMID: 30352677).