Glypican 2 Polyklonaler Antikörper

Glypican 2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27594-1-PBS

Synonyme

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  WB analysis using 27594-1-AP (same clone as 27594-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27594-1-AP (GPC2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27594-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27594-1-PBS bindet in WB, Indirect ELISA Glypican 2 und zeigt Reaktivität mit Maus, Ratten

• Getestete Reaktivität: Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Glypican 2 fusion protein Ag26734
• Vollständiger Name: glypican 2
• Berechnetes Molekulargewicht: 579 aa, 63 kDa
• Beobachtetes Molekulargewicht: 62-67 kDa
• GenBank-Zugangsnummer: BC027972
• Gene symbol: GPC2
• Gene ID (NCBI): 221914
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GPC2 (glypican 2), which is expected to be located in cell membrane and extracellular space. It is expressed in lymphoid tissue, skin and testis. The calculated molecular weight of the protein is 62 kDa. GPC2 is mainly active in growing nervous tissues and thyroid cancer tissues (PMID: 28616017). It participates in the growth and differentiation of neuronal axons. Increasing evidence has demonstrated the overexpression of GPC2 in neuroblastoma, a kind of childhood cancer. There is a discovery that GPC2 can be employed as a diagnostic, prognostic, and immunological predictor of generalized cancers. The study may broaden the train of thought toward application of GPC2 in immunotherapy (PMID: 35345673).