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Granzyme H Polyklonaler Antikörper

Granzyme H Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17228-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using Granzyme H Polyclonal antibody (17228-1-AP)

    WB analysis using 17228-1-AP (same clone as 17228-1-PBS)

    NK-92 cell lysates were subjected to SDS PAGE followed by western blot with 17228-1-AP (GZMH antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17228-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17228-1-PBS bindet in WB, Indirect ELISA Granzyme H und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Granzyme H fusion protein Ag11069
Vollständiger Name granzyme H (cathepsin G-like 2, protein h-CCPX)
Berechnetes Molekulargewicht 246 aa, 27 kDa
Beobachtetes Molekulargewicht~30 kDa
GenBank-ZugangsnummerBC027974
Gene symbol Granzyme H
Gene ID (NCBI) 2999
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Granzyme H (GzmH) belongs to a family of 5 human serine proteases that are expressed by cytotoxic immune effector cells. It's regarded as an orphan granzyme with unknown biologic functions in immune defense cells. It's reported that this serine protease is predominantly expressed at high levels in natural killer (NK) cells and has chymotrypsin-like (chymase) activity. The calculated molecular weight is 27 kDa, 17228-1-AP can detect a band around 30 kDa. (PMID: 17409270)