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H6PD Rekombinanter Antikörper

H6PD Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3C14

Kat-Nr. : 82819-2-PBS

Synonyme

6PGL, DKFZp686A01246, G6PDH, GDH, H6PD

Filter:
  • Western Blot (WB) analysis of various lysates using H6PD Recombinant antibody (82819-2-RR)

    WB analysis using 82819-2-RR (same clone as 82819-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82819-2-RR (H6PD antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82819-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82819-2-PBS bindet in WB, Indirect ELISA H6PD und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen H6PD fusion protein Ag7109
Vollständiger Name hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Berechnetes Molekulargewicht 89 kDa
Beobachtetes Molekulargewicht 89-95 kDa
GenBank-ZugangsnummerBC081559
Gene symbol H6PD
Gene ID (NCBI) 9563
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Hexose-6-phosphate dehydrogenase (H6PD) is also named as GDH,6PGL. It is the main NADPH generating enzyme in the lumen of the endoplasmic reticulum. H6PD is regarded as an ancillary enzyme in prereceptorial glucocorticoid activation and probably acts as a nutrient sensor and as a prosurvival factor(PMID:21620971). H6PD is a glycoprotein and has been shown tissue differences in glycosylation status might explain both the difference in migration on SDS-PAGE gels as well as in activity. Defects in H6PD are a cause of cortisone reductase deficiency (CRD).