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HAMP Polyklonaler Antikörper

HAMP Polyklonal Antikörper für WB, IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26237-1-PBS

Synonyme

HEPC, Hepc20, Hepc25 Hepcidin 20, HEPCIDIN, hepcidin antimicrobial peptide

Filter:
  • Western Blot (WB) analysis of various lysates using HAMP Polyclonal antibody (26237-1-AP)

    WB analysis using 26237-1-AP (same clone as 26237-1-PBS)

    HepG2 cells lysate was subjected to SDS PAGE followed by western blot with 26237-1-AP (HAMP antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26237-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of HepG2 cells using HAMP Polyclonal antibody (26237-1-AP)

    IP experiment of HepG2 using 26237-1-AP (same clone as 26237-1-PBS)

    IP result of anti-HAMP (IP:26237-1-AP, 4ug; Detection:26237-1-AP 1:500) with HepG2 cells lysate 1480 ug. This data was developed using the same antibody clone with 26237-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

26237-1-PBS bindet in WB, IP, ELISA HAMP und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HAMP fusion protein Ag24065
Vollständiger Name hepcidin antimicrobial peptide
Berechnetes Molekulargewicht 9 kDa
Beobachtetes Molekulargewicht12 kDa
GenBank-ZugangsnummerBC020612
Gene symbol HAMP
Gene ID (NCBI) 57817
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Hepcidin (HAMP) is a liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. It acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma (PMID: 22682227; 29237594; 32814342). Hepcidin is an 84-amino acid prepropeptide, and is usually cleaved into three peptide types, hepcidin-20, hepcidin-22, and hepcidin-25, of which hepcidin-25 is the active form and plays important roles in regulating functional iron deficiency (PMID: 34262329).