HAND2 Polyklonaler Antikörper

HAND2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21513-1-PBS

Synonyme

bHLHa26, dHand, DHAND2, Hed, Thing2

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  WB analysis using 21513-1-AP (same clone as 21513-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21513-1-AP (HAND2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21513-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

21513-1-PBS bindet in WB, Indirect ELISA HAND2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: HAND2 fusion protein Ag16038
• Vollständiger Name: heart and neural crest derivatives expressed 2
• Berechnetes Molekulargewicht: 217 aa, 24 kDa
• Beobachtetes Molekulargewicht: 30-35 kDa
• GenBank-Zugangsnummer: BC101406
• Gene symbol: HAND2
• Gene ID (NCBI): 9464
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HAND2 is a bHLH transcription factor essential for cardiac morphogenesis, neural crest differentiation, and limb development. Acting in the nucleus, it regulates gene networks shaping embryonic heart structure, craniofacial patterning, and limb polarity. Dysregulation of HAND2 is linked to congenital heart defects, craniofacial disorders, and certain cancers, highlighting its importance in both development and disease.