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HAPLN1 Polyklonaler Antikörper

HAPLN1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31646-1-PBS

Synonyme

Proteoglycan link protein, CRTL1, CRT1, Cartilage-linking protein 1, Cartilage-link protein

Filter:
  • Western Blot (WB) analysis of various lysates using HAPLN1 Polyclonal antibody (31646-1-AP)

    WB analysis using 31646-1-AP (same clone as 31646-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31646-1-AP (HAPLN1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31646-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31646-1-PBS bindet in WB, Indirect ELISA HAPLN1 und zeigt Reaktivität mit Maus, Ratten

Getestete Reaktivität Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HAPLN1 fusion protein Ag35652
Vollständiger Name hyaluronan and proteoglycan link protein 1
Berechnetes Molekulargewicht 40 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC057808
Gene symbol HAPLN1
Gene ID (NCBI) 1404
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HAPLN1 (hyaluronan and proteoglycan link protein 1), also known as CRTL1. It is expected to be located in the cytoplasm and extracellular, and the protein is mainly expressed in placenta and small intestine. The calculated molecular weight of HAPLN1 is 40 kDa. HAPLN1 binds to aggrecan on the hyaluronic chain, stabilizing the aggregates and thus increasing compression resistance and shock absorption. HAPLN1 also functions as a growth factor, up regulating aggrecan and type II collagen synthesis in cartilage. It seems to be an essential part of cartilage homeostasis and may also contribute to homeostasis in the disc tissue (PMID: 23537453).