HCN1 Rekombinanter Antikörper

HCN1 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242254A1

Kat-Nr. : 84845-3-PBS

Synonyme

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, HAC 2, Brain cyclic nucleotide-gated channel 1, BCNG-1, 242254A1

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  WB analysis using 84845-3-RR (same clone as 84845-3-PBS)

  Boiled and unboiled mouse brain tissue lysates were subjected to SDS PAGE followed by western blot with 84845-3-RR (HCN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84845-3-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 84845-3-RR (same clone as 84845-3-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 84845-3-RR (HCN1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84845-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

84845-3-PBS bindet in WB, IHC, Indirect ELISA HCN1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: hyperpolarization activated cyclic nucleotide-gated potassium channel 1
• Berechnetes Molekulargewicht: 99 kDa
• Beobachtetes Molekulargewicht: 99-120 kDa
• GenBank-Zugangsnummer: NM_021072
• Gene symbol: HCN1
• Gene ID (NCBI): 348980
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HCN1, also named as BCNG1, belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. HCN1 contributes to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP, and at 10-100 times higher concentrations, also by cGMP. HCN1 may mediate responses to sour stimuli.