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HCN4 Polyklonaler Antikörper

HCN4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55224-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using HCN4 Polyclonal antibody (55224-1-AP)

    WB analysis using 55224-1-AP (same clone as 55224-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55224-1-AP (HCN4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55224-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55224-1-PBS bindet in WB, Indirect ELISA HCN4 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name hyperpolarization activated cyclic nucleotide-gated potassium channel 4
Berechnetes Molekulargewicht 129 kDa
Beobachtetes Molekulargewicht140-160 kDa
GenBank-ZugangsnummerNM_005477
Gene symbol HCN4
Gene ID (NCBI) 10021
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HCN4 belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. HCN4 may contribute to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP. HCN4 may mediate responses to sour stimuli. (PMID:10228147). Defects in HCN4 are a cause of sick sinus syndrome type 2 (SSS2). Defects in HCN4 are the cause of Brugada syndrome type 8 (BRS8). This antibody is specific to HCN4.