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HCN4 Rekombinanter Antikörper

HCN4 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242695D11

Kat-Nr. : 85222-4-PBS

Synonyme

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, 242695D11

Filter:
  • Western Blot (WB) analysis of various lysates using HCN4 Recombinant antibody (85222-4-RR)

    WB analysis using 85222-4-RR (same clone as 85222-4-PBS)

    Mouse brain tissue lysates were subjected to SDS PAGE followed by western blot with 85222-4-RR (HCN4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85222-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85222-4-PBS bindet in WB, Indirect ELISA HCN4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name hyperpolarization activated cyclic nucleotide-gated potassium channel 4
Berechnetes Molekulargewicht 129 kDa
Beobachtetes Molekulargewicht 130 kDa
GenBank-ZugangsnummerNM_005477
Gene symbol HCN4
Gene ID (NCBI) 10021
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HCN4 belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. HCN4 may contribute to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP. HCN4 may mediate responses to sour stimuli. (PMID:10228147). Defects in HCN4 are a cause of sick sinus syndrome type 2 (SSS2). Defects in HCN4 are the cause of Brugada syndrome type 8 (BRS8).