HDAC1 Monoklonaler Antikörper

HDAC1 Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4C4G7

Kat-Nr. : 66085-1-PBS

Synonyme

4C4G7, EC:3.5.1.-, EC:3.5.1.98, GON 10, HD1



Geprüfte Anwendungen

Produktinformation

66085-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA HDAC1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen HDAC1 fusion protein Ag19128
Vollständiger Name histone deacetylase 1
Berechnetes Molekulargewicht 55 kDa
Beobachtetes Molekulargewicht 65 kDa
GenBank-ZugangsnummerBC000301
Gene symbol HDAC1
Gene ID (NCBI) 3065
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex, which is responsible for gene expression silencing. It also plays an important role in the control of cell proliferation and differentiation by interacting with RB, p53 and other transcription factors. At least 4 classes of HDAC were identified. As a class I HDAC, HDAC 1 was primarily found in the nucleus. This antibody is raised against residues near the C terminus of human HDAC1. The calculated molecular weight of HDAC1 is 55 kDa, but modified HDAC1 is about 60-65 kDa .