HDAC1 Monoklonaler Antikörper
HDAC1 Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
4C4G7
Kat-Nr. : 66085-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66085-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA HDAC1 und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | HDAC1 fusion protein Ag19128 |
Vollständiger Name | histone deacetylase 1 |
Berechnetes Molekulargewicht | 55 kDa |
Beobachtetes Molekulargewicht | 65 kDa |
GenBank-Zugangsnummer | BC000301 |
Gene symbol | HDAC1 |
Gene ID (NCBI) | 3065 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex, which is responsible for gene expression silencing. It also plays an important role in the control of cell proliferation and differentiation by interacting with RB, p53 and other transcription factors. At least 4 classes of HDAC were identified. As a class I HDAC, HDAC 1 was primarily found in the nucleus. This antibody is raised against residues near the C terminus of human HDAC1. The calculated molecular weight of HDAC1 is 55 kDa, but modified HDAC1 is about 60-65 kDa .