HDAC11 Monoklonaler Antikörper

HDAC11 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1G12B5

Kat-Nr. : 67949-1-PBS

Synonyme

FLJ22237, HD11, HDAC11, histone deacetylase 11

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  WB analysis using 67949-1-Ig (same clone as 67949-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67949-1-Ig (HDAC11 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

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  WB analysis of SKOV-3 using 67949-1-Ig (same clone as 67949-1-PBS)

  SKOV-3 cells were subjected to SDS PAGE followed by western blot with 67949-1-Ig (HDAC11 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary tumor using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67949-1-PBS bindet in WB, IHC, Indirect ELISA HDAC11 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: HDAC11 fusion protein Ag28335
• Vollständiger Name: histone deacetylase 11
• Berechnetes Molekulargewicht: 347 aa, 39 kDa
• Beobachtetes Molekulargewicht: 39 kDa
• GenBank-Zugangsnummer: BC009676
• Gene symbol: HDAC11
• Gene ID (NCBI): 79885
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. At least 4 classes of HDAC were identified. HDAC11 belongs to Class IV HDACs. HDAC11 is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 has 2 isoforms with the molecular mass of 33 and 39 kDa.