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HDAC3 Monoklonaler Antikörper

HDAC3 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3E8F10

Kat-Nr. : 67151-1-PBS

Synonyme

HD3, HDAC, HDAC3, histone deacetylase 3, RPD3, RPD3 2, SMAP45

Filter:
  • Western Blot (WB) analysis of various lysates using HDAC3 Monoclonal antibody (67151-1-Ig)

    WB analysis using 67151-1-Ig (same clone as 67151-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67151-1-Ig (HDAC3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67151-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HSC-T6 cells using HDAC3 Monoclonal antibody (67151-1-Ig)

    WB analysis of HSC-T6 using 67151-1-Ig (same clone as 67151-1-PBS)

    HSC-T6 cells were subjected to SDS PAGE followed by western blot with 67151-1-Ig (HDAC3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67151-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67151-1-PBS bindet in WB, Indirect ELISA HDAC3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen HDAC3 fusion protein Ag28464
Vollständiger Name histone deacetylase 3
Berechnetes Molekulargewicht 49 kDa
Beobachtetes Molekulargewicht49 kDa
GenBank-ZugangsnummerBC000614
Gene symbol HDAC3
Gene ID (NCBI) 8841
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the (-amino groups of lysines located near the amino termini of core histone proteins. At least 4 classes of HDAC were identified. HDAC3 is a class I HDAC. HDAC3 has histone deacetylase activity and may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. The gene encoding HDAC3 is regarded as a potential tumor suppressor gene.