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HDAC4-specific Monoklonaler Antikörper

HDAC4-specific Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

4C3B9

Kat-Nr. : 60105-1-Ig

Synonyme

Galerie der Validierungsdaten

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  • Western Blot (WB) analysis of human brain tissue using HDAC4-specific Monoclonal antibody (60105-1-Ig)

    WB analysis of human brain using 60105-1-Ig

    human brain tissue were subjected to SDS PAGE followed by western blot with 60105-1-Ig (HDAC4-specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60105-1-Ig bindet in ELISA HDAC4-specific und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name histone deacetylase 4
Berechnetes Molekulargewicht 119 kDa
GenBank-ZugangsnummerBC039904
Gene symbol HDAC4
Gene ID (NCBI) 9759
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Caprylsäure/Ammoniumsulfat-Präzipitation
Lagerungspuffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HDAC4, also named as HDACA, belongs to the histone deacetylase family. HDAC4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human HDAC4.

Publikationen

SpeciesApplicationTitle

Genes Dev

MEF2 transcription factors are key regulators of sprouting angiogenesis.

Authors - Natalia Sacilotto
View Article