HEBP2 Polyklonaler Antikörper

HEBP2 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12706-1-PBS

Synonyme

---

• 

  WB analysis of human brain using 12706-1-AP (same clone as 12706-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 12706-1-AP (HEBP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12706-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human kidney using 12706-1-AP (same clone as 12706-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 12706-1-AP (HEBP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12706-1-PBS in a different storage buffer formulation.

• 

  IP experiment of HEK-293 using 12706-1-AP (same clone as 12706-1-PBS)

  IP result of anti-HEBP2 (IP:12706-1-AP, 3ug; Detection:12706-1-AP 1:500) with HEK-293 cells lysate 2400ug. This data was developed using the same antibody clone with 12706-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

12706-1-PBS bindet in WB, IP, Indirect ELISA HEBP2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: HEBP2 fusion protein Ag3387
• Vollständiger Name: heme binding protein 2
• Berechnetes Molekulargewicht: 23 kDa
• Beobachtetes Molekulargewicht: 23 kDa
• GenBank-Zugangsnummer: BC008205
• Gene symbol: HEBP2
• Gene ID (NCBI): 23593
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HEBP2(Heme-binding protein 2), also named SOUL and C6orf34, can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions (PMID: 17098234). It is a 23 kDa haem-binding protein that was first identified as the PP23 protein isolated from human full-term placentas. hEBP2 is essential for the proliferation of human cells and the repression of hEBP2 severely decreases the ability of EBNA1 and EBV-based plasmids to bind mitotic chromosomes (PMID: 15923612).