HEXIM1 Monoklonaler Antikörper

HEXIM1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgM

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C8A2

Kat-Nr. : 66311-1-PBS

Synonyme

Hexamethylene bis-acetamide-inducible protein 1, Estrogen down-regulated gene 1 protein, EDG1, CLP1, CLP 1

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  WB analysis of Caco-2 using 66311-1-Ig (same clone as 66311-1-PBS)

  Caco-2 cells were subjected to SDS PAGE followed by western blot with 66311-1-Ig (HEXIM1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66311-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66311-1-Ig (same clone as 66311-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66311-1-Ig (HEXIM1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66311-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66311-1-Ig (same clone as 66311-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66311-1-Ig (HEXIM1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66311-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66311-1-PBS bindet in WB, Indirect ELISA HEXIM1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgM
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: HEXIM1 fusion protein Ag8019
• Vollständiger Name: hexamethylene bis-acetamide inducible 1
• Berechnetes Molekulargewicht: 41 kDa
• Beobachtetes Molekulargewicht: 54 kDa
• GenBank-Zugangsnummer: BC006460
• Gene symbol: HEXIM1
• Gene ID (NCBI): 10614
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Thiophiler Affinitätschromatograph
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HEXIM1, also named CLP1, EDG1, HIS1 or MAQ1, is best known as the inhibitor of positive transcription elongation factor b, which regulates the transcription elongation of RNA polymerase II and controls 60-70% of mRNA synthesis. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Previous studies showed that HEXIM1 interacts with two key p53 regulators, nucleophosmin and HDM2, implying a possible connection between HEXIM1 and the p53 signaling pathway.The mainstream MW of this protein is 65-70 kDa and 54 kDa ( PMID: 33627647, PMID: 20976203, PMID: 28254838).