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HIP14; ZDHHC17 Polyklonaler Antikörper

HIP14; ZDHHC17 Polyklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15465-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of Raji cells using HIP14; ZDHHC17 Polyclonal antibody (15465-1-AP)

    WB analysis of Raji using 15465-1-AP (same clone as 15465-1-PBS)

    Raji cells were subjected to SDS PAGE followed by western blot with 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human kidney tissue using HIP14; ZDHHC17 Polyclonal antibody (15465-1-AP)

    WB analysis of human kidney using 15465-1-AP (same clone as 15465-1-PBS)

    human kidney tissue were subjected to SDS PAGE followed by western blot with 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human testis tissue using HIP14; ZDHHC17 Polyclonal antibody (15465-1-AP)

    IHC staining of human testis using 15465-1-AP (same clone as 15465-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human testis using 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human testis tissue using HIP14; ZDHHC17 Polyclonal antibody (15465-1-AP)

    IHC staining of human testis using 15465-1-AP (same clone as 15465-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human testis using 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

15465-1-PBS bindet in WB, IHC, ELISA HIP14; ZDHHC17 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HIP14; ZDHHC17 fusion protein Ag7763
Vollständiger Name zinc finger, DHHC-type containing 17
Berechnetes Molekulargewicht 73 kDa
Beobachtetes Molekulargewicht 70 kDa
GenBank-ZugangsnummerBC050324
Gene symbol ZDHHC17
Gene ID (NCBI) 23390
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. ZDHHC17 gene encodes palmitoyl transferase huntingtin interacting protein (HIP14) which regulates palmitoylation and distribution of hungtingtin. The latter is implicated in the formation of inclusion bodies and enhanced neuronal toxicity. HIP14 was also shown to control neurotransmitter release.