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HIP14/ZDHHC17 Polyklonaler Antikörper

HIP14/ZDHHC17 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30022-1-PBS

Synonyme

HIP14; ZDHHC17, ZDHHC17, Acyltransferase ZDHHC17, DHHC 17, DHHC domain-containing cysteine-rich protein 17

Filter:
  • Western Blot (WB) analysis of various lysates using HIP14/ZDHHC17 Polyclonal antibody (30022-1-AP)

    WB analysis using 30022-1-AP (same clone as 30022-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30022-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30022-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using HIP14/ZDHHC17 Polyclonal antibody (30022-1-AP)

    WB analysis using 30022-1-AP (same clone as 30022-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30022-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30022-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using HIP14/ZDHHC17 Polyclonal antibody (30022-1-AP)

    IF Staining of U2OS using 30022-1-AP (same clone as 30022-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using HIP14; ZDHHC17 antibody (30022-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30022-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30022-1-PBS bindet in WB, IF/ICC, Indirect ELISA HIP14/ZDHHC17 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HIP14/ZDHHC17 fusion protein Ag32654
Vollständiger Name zinc finger, DHHC-type containing 17
Berechnetes Molekulargewicht 73 kDa
Beobachtetes Molekulargewicht 70 kDa
GenBank-ZugangsnummerBC050324
Gene symbol ZDHHC17
Gene ID (NCBI) 23390
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZDHHC17 is a neuronal palmitoyl transferase. Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. ZDHHC17 gene encodes palmitoyl transferase huntingtin interacting protein (HIP14) which regulates palmitoylation and distribution of hungtingtin. The latter is implicated in the formation of inclusion bodies and enhanced neuronal toxicity. HIP14 was also shown to control neurotransmitter release.