HIRA Polyklonaler Antikörper

HIRA Polyklonal Antikörper für IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31152-1-PBS

Synonyme



Geprüfte Anwendungen

Produktinformation

31152-1-PBS bindet in IP, Indirect ELISA HIRA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HIRA fusion protein Ag34439
Vollständiger Name HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
Berechnetes Molekulargewicht 112 kDa
Beobachtetes Molekulargewicht112 kDa
GenBank-ZugangsnummerNM_003325
Gene symbol HIRA
Gene ID (NCBI) 7290
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HIRA protein is encoded by a gene within a region of human chromosome 22q11.2 deleted in most patients with the DiGeorge syndrome, a developmental disorder, and was named for its amino acid sequence homology to two S. cerevisiae proteins, Hir1p and Hir2p. HIRA is critical in a specific chromatin assembly pathway that takes place independently of DNA synthesis (PMID: 12049744). HIRA complex associates with various proteins, such as transcription factors, RNA pol II, Prohibitin (PHB), and replication protein A (RPA) suggests that the targeting of the complex at specific locations may exploit additional structural properties and mechanisms (PMID: 30082790).