HLA-DMA Rekombinanter Antikörper

HLA-DMA Rekombinant Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230155D3

Kat-Nr. : 82899-1-PBS

Synonyme

230155D3, D6S222E, DMA, DMA protein, DMA protein MHC class II antigen Major histocompatibility complex, class II, DM alpha cDNA FLJ75740, highly similar to Homo sapiens major histocompatibility complex, class II, DM alpha

---

• 

  Cytometric bead array standard curve of MP00018-1

  Cytometric bead array standard curve of MP00018-1, HLA-DMA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82899-5-PBS. Detection antibody: 82899-1-PBS. Standard: Ag2452. Range: 0.625-20 ng/mL.

• 

  Cytometric bead array standard curve of MP00018-3

  Cytometric bead array standard curve of MP00018-3, HLA-DMA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82899-3-PBS. Detection antibody: 82899-1-PBS. Standard: Ag2452. Range: 0.625-20 ng/mL.

• 

  Affinity and Kinetic Characterization of 82899-1-RR

  Biolayer interferometry (BLl) kinetic assays of 82899-1-RR against Human HLA-DMA were performed. The affinity constant is below 1 pM.

---

Geprüfte Anwendungen

Produktinformation

82899-1-PBS bindet in Cytometric bead array, Indirect ELISA HLA-DMA und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: HLA-DMA fusion protein Ag2452
• Vollständiger Name: major histocompatibility complex, class II, DM alpha
• Berechnetes Molekulargewicht: 261 aa, 29 kDa
• GenBank-Zugangsnummer: BC026279
• Gene symbol: HLA-DMA
• Gene ID (NCBI): 3108
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). The class II molecules are composed of two non-covalently associated alpha and beta chains. HLA-DMA and HLA-DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.