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HLTF Rekombinanter Antikörper

HLTF Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Affe, human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251000A4

Kat-Nr. : 86362-2-PBS

Synonyme

DNA-binding protein/plasminogen activator inhibitor 1 regulator, EC:2.3.2.27, Helicase-like transcription factor, HIP116, HIP116A

Filter:
  • Western Blot (WB) analysis of various lysates using HLTF Recombinant monoclonal antibody (86362-2-RR)

    WB analysis using 86362-2-RR (same clone as 86362-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86362-2-RR (HLTF antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86362-2-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using HLTF Recombinant monoclonal antibody (86362-2-RR)

    WB analysis using 86362-2-RR (same clone as 86362-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86362-2-RR (HLTF antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86362-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86362-2-RR

    Affinity and Kinetic Characterization of 86362-2-RR

    Biolayer interferometry (BLl) kinetic assays of 86362-2-RR against Human HLTF were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

86362-2-PBS bindet in WB, Indirect ELISA HLTF und zeigt Reaktivität mit Affe, human, Maus

Getestete Reaktivität Affe, human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen HLTF fusion protein Ag5596
Vollständiger Name helicase-like transcription factor
Berechnetes Molekulargewicht 114 kDa
Beobachtetes Molekulargewicht 114 kDa
GenBank-ZugangsnummerBC044659
Gene symbol HLTF
Gene ID (NCBI) 6596
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Helicase-like Transcription Factor (HLTF) is a crucial nuclear protein and member of the SWI/SNF family of chromatin-remodeling complexes, playing a dual role in transcription regulation and DNA damage repair. It functions dually as a regulator of gene expression, utilizing its ATP-dependent helicase activity to modify chromatin structure and facilitate transcription, and as a central effector in the DNA damage response pathway. HLTF is particularly crucial for promoting error-free DNA repair at stalled replication forks via a mechanism called template switching, which prevents the accumulation of mutagenic lesions. HLTF can be detected as 114 kDa.