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HLX Polyklonaler Antikörper

HLX Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14336-1-PBS

Synonyme

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  • Western Blot (WB) analysis of human placenta tissue using HLX Polyclonal antibody (14336-1-AP)

    WB analysis of human placenta using 14336-1-AP (same clone as 14336-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 14336-1-AP (HLX antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14336-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human endometrial cancer tissue using HLX Polyclonal antibody (14336-1-AP)

    IHC staining of human endometrial cancer using 14336-1-AP (same clone as 14336-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer using 14336-1-AP (HLX antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14336-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human endometrial cancer tissue using HLX Polyclonal antibody (14336-1-AP)

    IHC staining of human endometrial cancer using 14336-1-AP (same clone as 14336-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer using 14336-1-AP (HLX antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14336-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A549 cells using HLX Polyclonal antibody (14336-1-AP)

    IF Staining of A549 using 14336-1-AP (same clone as 14336-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A549 cells using 14336-1-AP (HLX antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 14336-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14336-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA HLX und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HLX fusion protein Ag5627
Vollständiger Name H2.0-like homeobox
Berechnetes Molekulargewicht 51 kDa
Beobachtetes Molekulargewicht 51 kDa
GenBank-ZugangsnummerBC033808
Gene symbol HLX
Gene ID (NCBI) 3142
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

In immune system, Hlx is a Th1-special transcription factor that interacts specifically with T-bet, and synergistically they promote IFN-γ expression when co-expressed. It can down-regulate the IL-4 receptor expression in naive CD4+ T cells [PMID:14688316]. Over expression of Hlx contributes ot the aberrant expression of IFN-γ in normal CD4+ T cells during the differentiation under Th2-polarizing conditions. In addition, Hlx is a negative regulator of IFN-γ production in NK cells and its inhibitory function is achieved at least in part through the proteasomal degradation of STAT4 [PMID:16424184].