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HMGB4 Polyklonaler Antikörper

HMGB4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12787-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse testis tissue using HMGB4 Polyclonal antibody (12787-1-AP)

    WB analysis of mouse testis using 12787-1-AP (same clone as 12787-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 12787-1-AP (HMGB4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12787-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human testis tissue using HMGB4 Polyclonal antibody (12787-1-AP)

    WB analysis of human testis using 12787-1-AP (same clone as 12787-1-PBS)

    human testis tissue were subjected to SDS PAGE followed by western blot with 12787-1-AP (HMGB4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12787-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12787-1-PBS bindet in WB, Indirect ELISA HMGB4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HMGB4 fusion protein Ag3503
Vollständiger Name high-mobility group box 4
Berechnetes Molekulargewicht 186 aa, 22 kDa
Beobachtetes Molekulargewicht 22-25 kDa
GenBank-ZugangsnummerBC021180
Gene symbol HMGB4
Gene ID (NCBI) 127540
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

High mobility group protein B4 (HMGB4) is a new member in the family of HMGB proteins. Unlike other HMGB-proteins, it is a mammalian specific protein that has two HMGB-boxes but lacks the acidic tail. HMGB4 is strongly and preferentially expressed in the adult mouse testis and weakly in the brain, but not in many other tissues (PMID: 18987332). It binds strongly to nuclear structures, regulates chromatin and mediates differentiation of neuronal cells (PMID: 27608812).