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HMMR Monoklonaler Antikörper

HMMR Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C6B5

Kat-Nr. : 68718-1-PBS

Synonyme

RHAMM, Receptor for hyaluronan-mediated motility, Intracellular hyaluronic acid-binding protein, IHABP, CD168

Filter:
  • Western Blot (WB) analysis of various lysates using HMMR Monoclonal antibody (68718-1-Ig)

    WB analysis using 68718-1-Ig (same clone as 68718-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68718-1-Ig (HMMR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68718-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using HMMR Monoclonal antibody (68718-1-Ig)

    IF Staining of HepG2 using 68718-1-Ig (same clone as 68718-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using HMMR antibody (68718-1-Ig, Clone: 1C6B5 ) at dilution of 1:800 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 68718-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68718-1-PBS bindet in WB, IF/ICC, Indirect ELISA HMMR und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen HMMR fusion protein Ag33723
Vollständiger Name hyaluronan-mediated motility receptor (RHAMM)
Berechnetes Molekulargewicht84 kDa
Beobachtetes Molekulargewicht 84 kDa
GenBank-ZugangsnummerNM_012484
Gene symbol HMMR
Gene ID (NCBI) 3161
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Hyaluronan-mediated motility receptor (HMMR), also termed CD168, was first described by Turley in murine cells . It is reported that HMMR has an extensive coiled-coil structure (CC) that contains multiple sites for interactive partners. Initially, HMMR was considered a novel hyaluronan-mediated motility receptor and a microtubule-associated spindle assembly factor. Full-length human RHAMM is an 85  kDa coiled-coil protein that occurs both in intracellular and extracellular compartments. It has highly restricted and tightly regulated expression in most normal tissues, but is one of a number of oncogenic proteins that are exported to the cell surface in response to tissue stress by unconventional transport mechanisms. (PMID: 36750558, PMID: 30249497)