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HMMR-Specific Rekombinanter Antikörper

HMMR-Specific Rekombinant Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242332G4

Kat-Nr. : 85094-1-PBS

Synonyme

HMMR, 242332G4, CD168, IHABP, Intracellular hyaluronic acid-binding protein

Filter:
  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using HMMR-Specific Recombinant antibody (85094-1-RR)

    IHC staining of human tonsillitis using 85094-1-RR (same clone as 85094-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 85094-1-RR (HMMR-Specific antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85094-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using HMMR-Specific Recombinant antibody (85094-1-RR)

    IHC staining of human tonsillitis using 85094-1-RR (same clone as 85094-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 85094-1-RR (HMMR-Specific antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85094-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using HMMR-Specific Recombinant antibody (85094-1-RR)

    IF Staining of HepG2 using 85094-1-RR (same clone as 85094-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using HMMR-Specific antibody (85094-1-RR, Clone: 242332G4 ) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85094-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85094-1-PBS bindet in IHC, IF/ICC, Indirect ELISA HMMR-Specific und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name hyaluronan-mediated motility receptor (RHAMM)
Berechnetes Molekulargewicht 84 kDa
GenBank-ZugangsnummerNM_001142556
Gene symbol HMMR
Gene ID (NCBI) 3161
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Hyaluronan-mediated motility receptor (HMMR), also termed CD168, was first described by Turley in murine cells . It is reported that HMMR has an extensive coiled-coil structure (CC) that contains multiple sites for interactive partners. Initially, HMMR was considered a novel hyaluronan-mediated motility receptor and a microtubule-associated spindle assembly factor. Full-length human RHAMM is an 85  kDa coiled-coil protein that occurs both in intracellular and extracellular compartments. It has highly restricted and tightly regulated expression in most normal tissues, but is one of a number of oncogenic proteins that are exported to the cell surface in response to tissue stress by unconventional transport mechanisms. (PMID: 36750558, PMID: 30249497)