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HOGA1 Polyklonaler Antikörper

HOGA1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27755-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using HOGA1 Polyclonal antibody (27755-1-AP)

    WB analysis using 27755-1-AP (same clone as 27755-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27755-1-AP (HOGA1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27755-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27755-1-PBS bindet in WB, Indirect ELISA HOGA1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HOGA1 fusion protein Ag26849
Vollständiger Name chromosome 10 open reading frame 65
Beobachtetes Molekulargewicht35 kDa
GenBank-ZugangsnummerBC045550
Gene symbol HOGA1
Gene ID (NCBI) 112817
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HOGA1 (4-hydroxy-2-oxoglutarate aldolase), also known as C10orf65, DHDPSL, is a mitochondrial enzyme that plays a gatekeeper role in hydroxyproline metabolis. HOGA1 is primarily expressed in liver and kidney and catalyzes the final step of mitochondrial hydroxyproline metabolism\ from 4-hydroxy-2-oxoglutarate to glyoxylate and pyruvate (PMID: 31696211). Identification of mutations in the HOGA1 gene as the cause of autosomal recessive primary hyperoxaluria (PH) type III has revitalized research in the field of PH and related stone disease (PMID: 22781098).