HOMER3 Polyklonaler Antikörper

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• KD/KO Validated

HOMER3 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16624-1-PBS

Synonyme

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  WB analysis of mouse brain using 16624-1-AP (same clone as 16624-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 16624-1-AP (HOMER3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16624-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse lung using 16624-1-AP (same clone as 16624-1-PBS)

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 16624-1-AP (HOMER3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16624-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human brain using 16624-1-AP (same clone as 16624-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 16624-1-AP (HOMER3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16624-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat brain using 16624-1-AP (same clone as 16624-1-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 16624-1-AP (HOMER3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16624-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human cerebellum using 16624-1-AP (same clone as 16624-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cerebellum tissue slide using 16624-1-AP (HOMER3 antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 16624-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human cerebellum using 16624-1-AP (same clone as 16624-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cerebellum tissue slide using 16624-1-AP (HOMER3 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 16624-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

16624-1-PBS bindet in WB, IHC, Indirect ELISA HOMER3 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: HOMER3 fusion protein Ag9923
• Vollständiger Name: homer homolog 3 (Drosophila)
• Berechnetes Molekulargewicht: 361 aa, 40 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC012113
• Gene symbol: HOMER3
• Gene ID (NCBI): 9454
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HOMER3 is a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides.