HPGDS Rekombinanter Antikörper

HPGDS Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

242980B8

Kat-Nr. : 85446-2-RR

Synonyme

EC:2.5.1.18, EC:5.3.99.2, Glutathione S transferase, Glutathione S-transferase, Glutathione-dependent PGD synthase

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  WB analysis of human placenta using 85446-2-RR

  human placenta tissue were subjected to SDS PAGE followed by western blot with 85446-2-RR (HPGDS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 85446-2-RR

  Biolayer interferometry (BLl) kinetic assays of 85446-2-RR against Human HPGDS were performed. The affinity constant is 0.168 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Plazenta-Gewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

85446-2-RR bindet in WB, ELISA HPGDS und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: HPGDS fusion protein Ag18290
• Vollständiger Name: prostaglandin D2 synthase, hematopoietic
• Berechnetes Molekulargewicht: 199 aa, 23 kDa
• Beobachtetes Molekulargewicht: 26 kDa, 52 kDa
• GenBank-Zugangsnummer: BC020734
• Gene symbol: HPGDS
• Gene ID (NCBI): 27306
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Hematopoietic PGD synthase (HPGDS), one of the PGD2 synthases, is distributed in the cytoplasm of mast cells and Th2 cells and catalyzes PGD2 production during inflammation and allergic reactions. HPGDS belongs to the gene family of σ-type glutathione S-transferase (GST). Like other GSTs, it exists as a homodimer in vivo with a molecular weight of approximately 52 kDa (PMID: 38339125).