HSP27 Rekombinanter Antikörper

HSP27 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250818H6

Kat-Nr. : 80046-5-PBS

Synonyme

HSPB1, CMT2F, Estrogen-regulated 24 kDa protein, HMN2B, Hsp25

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  WB analysis using 80046-5-RR (same clone as 80046-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 80046-5-RR (HSP27 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80046-5-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

80046-5-PBS bindet in WB, Indirect ELISA HSP27 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: HSP27 fusion protein Eg4620
• Vollständiger Name: heat shock 27kDa protein 1
• Berechnetes Molekulargewicht: 23kDa
• Beobachtetes Molekulargewicht: 27 kDa
• GenBank-Zugangsnummer: NM_001540.5
• Gene symbol: HSPB1
• Gene ID (NCBI): 3315
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HSPB1, also known as heat shock protein 27 (HSP27), belongs to the small heat shock protein family which is induced in response to environmental challenges or/and developmental transitions. It is also an anti-apoptotic protein that plays crucial roles in tumorigenesis and cell survival and is reported to be an independent prognosis marker for cancer. Recently HSPB1 has been found to be a valuable marker for melanoma. In addition to the predicted 27 kDa, an extra 50-55 kDa representing dimeric form of HSPB1 may also be observed (PMID: 21353161). It's notable that mouse HSP27 is also named HSP25 and has the predicted MW between 19-23 kDa.