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HSPA1B Rekombinanter Antikörper

HSPA1B Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242371E8

Kat-Nr. : 84873-4-PBS

Synonyme

242371E8, HSP72

Filter:
  • Western Blot (WB) analysis of various lysates using HSPA1B Recombinant antibody (84873-4-RR)

    WB analysis using 84873-4-RR (same clone as 84873-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84873-4-RR (HSPA1B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84873-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84873-4-RR

    Affinity and Kinetic Characterization of 84873-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84873-4-RR against Human HSPA1B were performed. The affinity constant is 9.62 nM.

Geprüfte Anwendungen

Produktinformation

84873-4-PBS bindet in WB, Indirect ELISA HSPA1B und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen HSPA1B fusion protein Ag13700
Vollständiger Name heat shock 70kDa protein 1B
Berechnetes Molekulargewicht 70 kDa
Beobachtetes Molekulargewicht 70 kDa
GenBank-ZugangsnummerBC057397
Gene symbol HSP70
Gene ID (NCBI) 3304
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HSP70 (also referred to HSP72), is a stress-inducible member of heat-shock protein 70 (HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSP70 is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSP70 is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSP70 protein can be highly activated by various stressful stimuli. Significant up-regulation of HSP70 has been found in various tumors. Recently it has been reported that HSP70 can be constitutively expressed in selected cell types. HSP70 is also used as exosomal marker.