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HSPB11 Polyklonaler Antikörper

HSPB11 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15732-1-PBS

Synonyme



Geprüfte Anwendungen

Produktinformation

15732-1-PBS bindet in WB, Indirect ELISA HSPB11 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HSPB11 fusion protein Ag8490
Vollständiger Name heat shock protein family B (small), member 11
Berechnetes Molekulargewicht 144 aa, 16 kDa
Beobachtetes Molekulargewicht 16-20 kDa
GenBank-ZugangsnummerBC005245
Gene symbol HSPB11
Gene ID (NCBI) 51668
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.