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HSPB11 Monoklonaler Antikörper
HSPB11 Monoklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2D11B3
Kat-Nr. : 68059-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
68059-1-PBS bindet in WB, Indirect ELISA HSPB11 und zeigt Reaktivität mit human
| Getestete Reaktivität | human | 
| Wirt / Isotyp | Maus / IgG2a | 
| Klonalität | Monoklonal | 
| Typ | Antikörper | 
| Immunogen | HSPB11 fusion protein Ag8804 | 
| Vollständiger Name | heat shock protein family B (small), member 11 | 
| Berechnetes Molekulargewicht | 144 aa, 16 kDa | 
| Beobachtetes Molekulargewicht | 20 kDa | 
| GenBank-Zugangsnummer | BC005245 | 
| Gene symbol | HSPB11 | 
| Gene ID (NCBI) | 51668 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Protein-A-Reinigung | 
| Lagerungspuffer | PBS only | 
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.



