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HTR7 Polyklonaler Antikörper

HTR7 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13830-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using HTR7 Polyclonal antibody (13830-1-AP)

    WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 13830-1-AP (HTR7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse spleen tissue using HTR7 Polyclonal antibody (13830-1-AP)

    WB analysis of mouse spleen using 13830-1-AP (same clone as 13830-1-PBS)

    mouse spleen tissue were subjected to SDS PAGE followed by western blot with 13830-1-AP (HTR7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using HTR7 Polyclonal antibody (13830-1-AP)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using HTR7 Polyclonal antibody (13830-1-AP)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13830-1-PBS bindet in WB, IHC, Indirect ELISA HTR7 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HTR7 fusion protein Ag4742
Vollständiger Name 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
Berechnetes Molekulargewicht 445 aa, 49 kDa
Beobachtetes Molekulargewicht 50-55 kDa
GenBank-ZugangsnummerBC047526
Gene symbol HTR7
Gene ID (NCBI) 3363
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Serotonin (5-hydroxytryptamine; 5-HT) acts as a neurotransmitter and neuromodulator in the central nervous system(CNS) (PMID:23100172). The behavioral effects of 5-HT are mediated by a large family of specific 5-HT receptors. HTR7 (5-hydroxytryptamine receptor 7) is a G protein-coupled receptor (GPCR), and many transcription factors can bind to its promoter, such as AP2, EGR-1, and MAZ (PMID:34164474). It is located in different brain regions, such as the hypothalamus, thalamus, cerebral cortex, and hippocampus (PMID:29637287). HTR7 is associated with circadian rhythm, anxiety, depression, schizophrenia, nociception, and memory (PMID:9154233).