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HTRA3 Polyklonaler Antikörper

HTRA3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31369-1-PBS

Synonyme

Tasp, PRSP

Filter:
  • Western Blot (WB) analysis of various lysates using HTRA3 Polyclonal antibody (31369-1-AP)

    WB analysis using 31369-1-AP (same clone as 31369-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31369-1-AP (HTRA3 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31369-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31369-1-PBS bindet in WB, Indirect ELISA HTRA3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HTRA3 fusion protein Ag35448
Vollständiger Name HtrA serine peptidase 3
Berechnetes Molekulargewicht49kDa，453aa
Beobachtetes Molekulargewicht49 kDa
GenBank-ZugangsnummerNM_053044.4
Gene symbol HTRA3
Gene ID (NCBI) 94031
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HTRA3 is one of the four members of the HtrA family proteins, with a secreted multidomain and serine protease activity, which plays an important role in cellular stress response, protein homeostasis, and apoptosis. HTRA3 is highly expressed in the decidual cells in the late secretory phase of the menstrual cycle and throughout pregnancy, and in most trophoblast cell types, apart from the invading interstitial trophoblast during the first trimester. HTRA3 and its family members are down-regulated in several cancers and are proposed as tumor suppressors (PMID: 21321049, 22229724).