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HURP Polyklonaler Antikörper

HURP Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12038-1-PBS

Synonyme

DAP-5, Discs large homolog 7, Disks large-associated protein 5, Disks large-associated protein DLG7, DLG7

Filter:
  • Western Blot (WB) analysis of various lysates using HURP Polyclonal antibody (12038-1-AP)

    WB analysis using 12038-1-AP (same clone as 12038-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12038-1-AP (HURP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12038-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HEK-293 cells using HURP Polyclonal antibody (12038-1-AP)

    IF Staining of HEK-293 using 12038-1-AP (same clone as 12038-1-PBS)

    Immunofluorescent analysis of (10% Formaldehyde) fixed HEK-293 cells using 12038-1-AP (HURP antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 12038-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12038-1-PBS bindet in WB, IF/ICC, Indirect ELISA HURP und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen HURP fusion protein Ag2667
Vollständiger Name discs, large (Drosophila) homolog-associated protein 5
Berechnetes Molekulargewicht 846 aa, 95 kDa
Beobachtetes Molekulargewicht120 kDa
GenBank-ZugangsnummerBC010658
Gene symbol HURP
Gene ID (NCBI) 9787
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DLGAP5, also named as DAP 5 or DLG7, is a kinetochore protein that stabilizes microtubules in vicinity of chromosomes. DLG7 controls spindle dynamics, promotes interkinetochore tension and efficient kinetochore capture. DGL7 is a part of Ran-dependent complex. Expression of DGL7 is found in cancer and stem cells. DLGAP5 contributes to hepatocellular carcinoma tumorigenesis by promoting cell proliferation (PMID: 24324629).