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HVEM/TNFRSF14 Rekombinanter Antikörper

HVEM/TNFRSF14 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250728B12

Kat-Nr. : 81078-6-PBS

Synonyme

TNFRSF14, ATAR, CD270, Herpes virus entry mediator A, Herpesvirus entry mediator A

Filter:
  • Western Blot (WB) analysis of human urine sample using HVEM/TNFRSF14 Recombinant antibody (81078-6-RR)

    WB analysis of human urine using 81078-6-RR (same clone as 81078-6-PBS)

    human urine sample was subjected to SDS PAGE followed by western blot with 81078-6-RR (HVEM/TNFRSF14 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81078-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 81078-6-RR

    Affinity and Kinetic Characterization of 81078-6-RR

    Biolayer interferometry (BLl) kinetic assays of 81078-6-RR against Human HVEM/TNFRSF14 were performed. The affinity constant is 3.00 nM.

Geprüfte Anwendungen

Produktinformation

81078-6-PBS bindet in WB, Indirect ELISA HVEM/TNFRSF14 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen HVEM/TNFRSF14 fusion protein Eg1275
Vollständiger Name tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Berechnetes Molekulargewicht 30 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC002794
Gene symbol TNFRSF14
Gene ID (NCBI) 8764
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes.