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Histone H3 (C-terminal) Monoklonaler Antikörper

Histone H3 (C-terminal) Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Huhn, human, Maus, Ratte, wheat, Zebrafisch

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2G10C3

Kat-Nr. : 68503-1-PBS

Synonyme

HIST1H3A, 2G10C3, Histone-H3, HistoneH3, Histone H3

Filter:
  • Western Blot (WB) analysis of various lysates using Histone H3 (C-terminal) Monoclonal antibody (68503-1-Ig)

    WB analysis using 68503-1-Ig (same clone as 68503-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68503-1-Ig (HIST1H3A antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68503-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse testis tissue using Histone H3 (C-terminal) Monoclonal antibody (68503-1-Ig)

    IHC staining of mouse testis using 68503-1-Ig (same clone as 68503-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 68503-1-Ig (HIST1H3A antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68503-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse testis tissue using Histone H3 (C-terminal) Monoclonal antibody (68503-1-Ig)

    IHC staining of mouse testis using 68503-1-Ig (same clone as 68503-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 68503-1-Ig (HIST1H3A antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68503-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68503-1-PBS bindet in WB, IHC, Indirect ELISA Histone H3 (C-terminal) und zeigt Reaktivität mit Huhn, human, Maus, Ratten, wheat, Zebrafisch

Getestete Reaktivität Huhn, human, Maus, Ratte, wheat, Zebrafisch
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name histone cluster 1, H3a
Beobachtetes Molekulargewicht15 kDa
GenBank-ZugangsnummerBC066245
Gene symbol HIST1H3A
Gene ID (NCBI) 8350
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Histones are small, highly basic proteins that consist of a globular domain with unstructured N- and C-terminal tails protruding from the main structure. Histone H3 is one of the five main histones that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. In addition to their role in DNA compartmentalization, histones also play crucial roles in various biologic processes, including gene expression and regulation, DNA repair, chromatin condensation, cell cycle progression, chromosome segregation, and apoptosis. The ability of histones to regulate chromatin dynamics primarily originates from various posttranslational modifications carried out by histone-modifying enzymes.